Pilocarpine

 Pilocarpine Dissertation

pilocarpine (Fig. 5), 0. 45 mg. per kilogram

of atropine was administered intraperitoneally. Nine moments after the atropine, the myopia had improved and then remained high right up until a larger dosage of atropine, 0. almost 8 mg. every kilogram, was given. The pupil contracted maximally during the try things out, and dilated only following your second dose of atropine. The exceptional fluctuations in refraction after 50 magnesium. per kilogram pilocarpine (Fig. 5) are not due topilocarpine (Fig. 5), 0. 45 mg. per kilogram of atropine was administered intraperitoneally. Nine minutes after the atropine, the myopia had elevated and then continued to be high till a larger dosage of atropine, 0. 8 mg. every kilogram, was given. The scholar contracted maximally during the experiment, and dilated only after the second dosage of atropine. The impressive fluctuations in refraction after 50 mg. per kilogram pilocarpine (Fig. 5) are not due to errors of measurements. Each point is in

simple fact the average of several readings in speedy

succession and no doubt that real

fluctuations of refraction took place. The

same holds true for the dip in 11 moments after

the first atropine dose. This was the only

monkey in the present series in which right now there

were such fluctuations and the only one

which showed this paradoxical impact on

refraction with pilocarpine and atropine.

Changes in refraction have sometimes

been found after systemic carbachol, and

with this drug the paradoxical effect on refraction is constantly mentioned after high doses.

6th

Systemic associated with pilocarpine. The monkeys began to salivate following 0. 1 mg. every kilogram of pilocarpine. By 0. five to 1. zero mg.

per kilogram the salivation was profuse an

errors of measurements. Each point is at

fact the regular of many readings in rapid

sequence and there is no doubt that true

fluctuations of refraction happened. The

same is true pertaining to the dip at 10 minutes following

the first atropine dose. This was the only

monkey in the present series by which there...


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